"Emotional engineering to anticipate early treatment dropout."

The Problem: dropout is not technical—it is emotional

The molecule may be right. The protocol may be right. The therapeutic bond breaks earlier.

The Problem

Lo que el laboratorio sabe vs. lo que no ve

Lo que sabe

They know the drug works and the protocol is correct.

Lo que no ve

They do not see the moment fear defeats hope, or frustration erodes adherence.

Por qué la emoción domina la conducta

A meaningful portion of dropout is not explained by cost or side effects, but by emotional and cognitive variables.

"If today that needle is at zero, even incremental movement changes outcomes."

The early critical window

The first weeks are decisive; early signals are weak but detectable when emotional trajectories are modeled.

Critical Window